Seeking partition advice in single OS system

The partition discussion I've seen here seems mostly to deal with dual boot operating systems.  I'm getting a system with Vista 64 bit, and, at least for now, the plan is to have only that OS.  I'm looking for advice as to how to best partition my drives (if at all) when my system arrives.

I have a 150 GB Raptor (10K RPM), and a 500 GB 7200 RPM drive.  I do some video editing (family videos, not professional), hence the large second drive.  Gaming and video editing will be my two main uses for this system.

For what it is worth, on my current rig (to be replaced by my DS rig when it arrives), I've just been using an external USB drive as my video capture drive, and have been putting all my Adobe Premiere project data on that drive.  The exception is some sound files that are stored on an internal drive (with "F" as its drive letter).  To copy the projects over to the new machine, I figure I can just plug in the USB drive and make sure the drive letter is mapped the same as on the old machine.  That will work for all but the sound files.  If I copy the sound files from the old machine onto a drive on the new system that is not labeled as the "F" drive, I suspect that Premiere will make me manually locate each sound file that a project calls for, the first time I open that project.  To avoid this, I was thinking about creating an "F" partition on the new system, so I could just copy the sound files over.  Then, all my drive letter assignments would match my old system.  (Does this make sense?)

Any thoughts on my (long-winded) plans, and suggestions for partitions if any?  Thanks!

I also have the same 150 + 500 Gig set up (plus another 500 Gig external) set up as follows:

• C: 50 Gig for XP and applications like Word
• D:100 Gig for games
• E: 250 Gig Data
• F: 250 Gig Video & Music

Frankly, I don't think it makes any difference for performance, but I like to keep the OS and "real" computer stuff isolated on it's own partition just for my own mental organization and for quicker defragmenting.

I also don't think you can avoid configuring all your newly reinstalled applications to tell them where their data is. None of that kind of structure is going to survive the move to the new machine.

Thanks for all the suggestions!  Quick question- is it a big deal to remap (i.e. re-letter) my 2 optical drives, if I do it before I start installing stuff?  I'd like to keep all my hard drives sequential.  Will that mess anything up?  I know if I do it AFTER I install certain games, that can cause problems for games that require the disc to be in the drive.  Any other issues I should be aware of?